姓名：倪苏婕
职称：副教授
个人简介：江苏南通人，医学博士（肿瘤学）。
专业研究领域：恶性肿瘤精准化疗，分子靶向治疗，免疫治疗
专著与论集：
1) Yang C, Jia Y, Zhao T, Xue Y, Zhao Z, Zhang J, Wang J, Wang X, Qiu Y, Lin M, Zhu D, Qi G, Qiu Y, Tang Q, Rong R, Xu M, Ni S, Lai B, Nicholson ML, Zhu T, Yang B. Naked caspase 3 small interfering RNA is effective in cold preservation but not in autotransplantation of porcine kidneys. J Surg Res. 2013 May;181(2):342-54.
2) 赵丽琴,郭伟剑,张晓伟,屈晓飞,王小凤,倪苏婕,黄明主.CBX7在胃癌干细胞样细胞中的表达及其功能研究[J].中国癌症杂志,2013,23(02):114-119.
3) Ni S, Zhu J, Zhang J, Zhang S, Li M, Ni R, Liu J, Qiu H, Chen W, Wang H, Guo W. Expression and clinical role of NF45 as a novel cell cycle protein in esophageal squamous cell carcinoma (ESCC). Tumor Biology. 2015 Feb;36(2):747-56.
4) Chen L, Ni S, Li M, Shen C, Lin Z, Ouyang Y, Xia F, Liang L, Jiang W, Ni R, Zhang J. High Expression of BCCIP β Can Promote Proliferation of Esophageal Squamous Cell Carcinoma. Digestive Diseases and Sciences. 2015, 38(15)30046-7.
5) Zhang XW, Wang XF, Ni SJ, Qin W, Zhao LQ, Hua RX, Lu YW, Li J, Dimri GP, Guo WJ*. UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop. J Pathol. 2015 Mar;235(4):656-67.
6) Lu Y, Ni S, He LN, Gao YJ, Jiang BC. Annexin A10 is involved in the development and maintenance of neuropathic pain in mice. Neurosci Lett. 2016 Sep 19;631:1-6.
7) Ni S, Wang H, Zhu X, Wan C, Xu J, Lu C, Xiao L, He J, Jiang C, Wang W, He Z. CBX7 suppresses cell proliferation, migration, and invasion through the inhibition of PTEN/Akt signaling in pancreatic cancer. Oncotarget. 2016 Dec 20.
8) Ni S, Chen L, Li M, Zhao W, Shan X, Wu M, Cheng J, Liang L, Wang Y, Jiang W, Zhang J, Ni R. PKC iota promotes cellular proliferation by accelerated G1/S transition via interaction with CDK7 in esophageal squamous cell carcinoma. Tumor Biology. 2016 Oct;37(10):13799-13809.
9) 倪苏婕.临床教学模式改革中实行本科生导师制的实践与思考[J].时代教育,2016(19):197.
10) Wang X, Wang C, Zhang X, Hua R, Gan L, Huang M, Zhao L, Ni S, Guo W. Bmi-1 regulates stem cell-like properties of gastric cancer cells via modulating miRNAs. J Hematol Oncol. 2016 Sep 20;9(1):90. doi: 10.1186/s13045-016-0323-9.
11) Chen L, Ni S, Li M, Shen C, Lin Z, Ouyang Y, Xia F, Liang L, Jiang W, Ni R, Zhang J. High Expression of BCCIP β Can Promote Proliferation of Esophageal Squamous Cell Carcinoma. Dig Dis Sci. 2017 Feb;62(2):387-395.
12) Ni SJ, Zhao LQ, Wang XF, Wu ZH, Hua RX, Wan CH, Zhang JY, Zhang XW, Huang MZ, Gan L, Sun HL, Dimri GP, Guo WJ. CBX7 regulates stem cell-like properties of gastric cancer cells via p16 and AKT-NF-κB-miR-21 pathways. J Hematol Oncol. 2018 Feb 8;11(1):17.
13) He Z, Wang F, Zhang W, Ding J, Ni S. Comprehensive and integrative analysis identifies COX7A1 as a critical methylation-driven gene in breast invasive carcinoma. Ann Transl Med. 2019 Nov;7(22):682. doi: 10.21037/atm.2019.11.97.
14) Chen L, Wang Y, Jiang W, Ni R, Wang Y, Ni S. CDK14 involvement in proliferation migration and invasion of esophageal cancer. Ann Transl Med. 2019 Nov;7(22):681. doi: 10.21037/atm.2019.11.105. Erratum in: Ann Transl Med. 2020 Apr;8(8):559.
15) He Z, Zhou Y, Wang F, Xu Q, Zhang W, Ni X, Ni S. Clinical value of postoperative sentinel lymph node biopsy. Ann Transl Med. 2019 Nov;7(22):683. doi: 10.21037/atm.2019.11.106. Erratum in: Ann Transl Med. 2020 Apr;8(7):519.
16) Yao N, Zuo L, Yan X, Qian J, Sun J, Xu H, Zheng F, Efird JT, Kawagoe I, Wang Y, Ni S. Systematic analysis of ferroptosis-related long non-coding RNA predicting prognosis in patients with lung squamous cell carcinoma. Transl Lung Cancer Res. 2022 Apr;11(4):632-646.
17) 倪苏婕,高健林,沈树泉.肥胖和高甘油三酯血症与重症新型冠状病毒肺炎及其死亡相关联的临床证据及可能机制[J].生理学报,2022,74(05):783-791.
18) Zhong X, Xu S, Wang Q, Peng L, Wang F, He T, Liu C, Ni S, He Z. CAPN8 involves with exhausted, inflamed, and desert immune microenvironment to influence the metastasis of thyroid cancer. Front Immunol. 2022 Oct 27;13:1013049.
19) He Z, Zhou Z, Wang F, Gai L, Huang Y, Zhong X, Li J, Zuo L, Zhang N, Ni S. Comprehensive analysis of the relationship between the ferroptosis and tumor-infiltrating immune cells, mutation, and immunotherapy in breast cancer. Ann Transl Med. 2022 Aug;10(15):833.
20) Ke J, Wang Q, Zhang W, Ni S, Mei H. LncRNA MIR4435-2HG promotes proliferation, migration, invasion and epithelial mesenchymal transition via targeting miR-22-3p/TMEM9B in breast cancer. Am J Transl Res. 2022 Aug 15;14(8):5441-5454.
21) 胡志德,倪苏婕,周承志,陈天翔,何雅億,李亮,刘哲,沈建飞,杨洋.临床研究经典案例分析.中南大学出版社,2021. (ISBN9787548743590,中国)
主要科研项目
1、主持国家自然科学基金项目1项
国家自然科学基金委员会, 青年科学基金项目, 81702608, ATPIF1促进三阴性乳腺癌转移的机制研究，2018-01-01 至 2020-12-31, 20万元, 结题, 主持
2、主持市级科研项目2项
1) 南通市科学技术局, 科技计划项目, JC2019144, AR对SUMO1介导的蛋白SUMO化修饰在三阴性乳腺癌中的调节作用, 2019-07 至 2021-06, 6万元, 结题, 主持
2) 南通市科学技术局, 科技计划项目, MS22016068, MiR-203与CDK/CCNH复合物调控CDK14参与食管癌发生发展的机制研究, 2016-10 至 2018-09, 6万元, 结题, 主持
讲授课程
肿瘤内科学，诊断学
指导研究生情况
已毕业硕士生研究生5名；在读硕士生1名。